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EN2 抗体 (AA 281-333) (AbBy Fluor® 350)

EN2 适用: 人, 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1391943
发货至: 中国
  • 抗原 See all EN2 抗体
    EN2 (Engrailed Homeobox 2 (EN2))
    抗原表位
    • 18
    • 14
    • 13
    • 5
    • 1
    AA 281-333
    适用
    • 59
    • 30
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 56
    • 2
    • 1
    克隆类型
    • 57
    • 2
    多克隆
    标记
    • 21
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EN2 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 48
    • 28
    • 12
    • 12
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EN2/Engrailed 2
    亚型
    IgG
    Top Product
    Discover our top product EN2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EN2 (Engrailed Homeobox 2 (EN2))
    别名
    EN2/Engrailed 2 (EN2 产品)
    别名
    EN2 antibody, en antibody, en2 antibody, BB131122 antibody, En-2 antibody, RGD1561842 antibody, Gg-En-2 antibody, engrailed homeobox 2 antibody, engrailed homeobox antibody, engrailed 2 antibody, EN2 antibody, en antibody, En2 antibody
    背景

    Synonyms: Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2

    Background: The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson?s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.

    基因ID
    2020
    UniProt
    P19622
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