NPS 抗体 (AA 70-89) (AbBy Fluor® 555)
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- 抗原 See all NPS 抗体
- NPS (Neuropeptide S (NPS))
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抗原表位
- AA 70-89
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPS antibody is conjugated to AbBy Fluor® 555
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Neuropeptide S
- 亚型
- IgG
- Top Product
- Discover our top product NPS Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- NPS (Neuropeptide S (NPS))
- 别名
- NPS/Neuropeptide S (NPS 产品)
- 别名
- ENSMUSG00000073804 antibody, neuropeptide S antibody, NPS antibody, Nps antibody
- 背景
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Synonyms: NeuropeptideS, Neuropeptide-S, NPS, NPS_HUMAN.
Background: Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
- 基因ID
- 594857
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