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Utrophin 抗体 (AbBy Fluor® 350)

UTRN 适用: 人, 小鼠, 大鼠 FACS 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1391013
发货至: 中国
  • 抗原 See all Utrophin (UTRN) 抗体
    Utrophin (UTRN)
    适用
    人, 小鼠, 大鼠
    宿主
    • 13
    • 3
    克隆类型
    • 14
    • 2
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Utrophin antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Utrophin
    亚型
    IgG
    Top Product
    Discover our top product UTRN Primary Antibody
  • 应用备注
    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Utrophin (UTRN)
    别名
    Utrophin (UTRN 产品)
    别名
    drp antibody, dmdl antibody, drp1 antibody, DKFZp469A0710 antibody, DMDL antibody, DRP antibody, DRP1 antibody, AA589569 antibody, Dmdl antibody, utrophin L homeolog antibody, utrophin antibody, utrn.L antibody, UTRN antibody, LOAG_03796 antibody, utrn antibody, LOC100551145 antibody, Utrn antibody
    背景

    Synonyms: DMDL, DRP 1, DRP, DRP-1, DRP1, Dystrophin like protein, Dystrophin related protein 1, Dystrophin related protein, Dystrophin-related protein 1, FLJ23678, UTRN, UTRO_HUMAN, Utrophin homologous to dystrophin, Utrophin

    Background: Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.

    基因ID
    7402
    途径
    Skeletal Muscle Fiber Development
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