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Synaptojanin 2 抗体 (AA 401-500) (Biotin)

SYNJ2 适用: 人 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1390915
发货至: 中国
  • 抗原 See all Synaptojanin 2 (SYNJ2) 抗体
    Synaptojanin 2 (SYNJ2)
    抗原表位
    • 14
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    适用
    • 40
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 4
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Synaptojanin 2 antibody is conjugated to Biotin
    应用范围
    • 33
    • 13
    • 13
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Synaptojanin 2
    亚型
    IgG
    Top Product
    Discover our top product SYNJ2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Synaptojanin 2 (SYNJ2)
    别名
    Synaptojanin 2 (SYNJ2 产品)
    别名
    SYNJ2 antibody, INPP5H antibody, AI481647 antibody, SJ2 antibody, mKIAA0348 antibody, synaptojanin 2 antibody, synaptojanin-2 antibody, SYNJ2 antibody, LOC100074269 antibody, synj2 antibody, Synj2 antibody
    背景

    Synonyms: 5-trisphosphate 5-phosphatase 2, Inositol phosphate 5' phosphatase 2, INPP 5H, INPP5H, KIAA0348, MGC44422, SJ2, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, SYNJ 2, Synj2, SYNJ2_HUMAN.

    Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

    基因ID
    8871
    途径
    Inositol Metabolic Process
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