C1QC 抗体 (AA 81-180) (AbBy Fluor® 488)
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- 抗原 See all C1QC 抗体
- C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))
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抗原表位
- AA 81-180
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C1QC antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C1QC
- 亚型
- IgG
- Top Product
- Discover our top product C1QC Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))
- 别名
- C1QC/C1QG (C1QC 产品)
- 别名
- c1qc antibody, AI385742 antibody, C1qg antibody, Ciqc antibody, C1Q-C antibody, C1QG antibody, complement C1q C chain antibody, complement component 1, q subcomponent, C chain antibody, C1QC antibody, c1qc antibody, C1qc antibody
- 背景
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Synonyms: C1Q C, C1qc, C1QC_HUMAN, C1QG, Complement C1q subcomponent subunit C, Complement component 1, q subcomponent, C chain, complement component 1, q subcomponent, gamma polypeptide, AI385742.
Background: C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA, as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms.
- 途径
- Complement System
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