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ATXN7 抗体 (AA 301-400) (AbBy Fluor® 488)

ATXN7 适用: 小鼠, 大鼠 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1390558
发货至: 中国
  • 抗原 See all ATXN7 抗体
    ATXN7 (Ataxin 7 (ATXN7))
    抗原表位
    • 14
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 35
    • 27
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 48
    • 1
    克隆类型
    • 48
    • 1
    多克隆
    标记
    • 16
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATXN7 antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 38
    • 23
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Ataxin 7
    亚型
    IgG
    Top Product
    Discover our top product ATXN7 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ATXN7 (Ataxin 7 (ATXN7))
    别名
    Ataxin 7 (ATXN7 产品)
    别名
    MGC82940 antibody, ADCAII antibody, OPCA3 antibody, SCA7 antibody, A430107N12Rik antibody, AI627028 antibody, Sca7 antibody, ataxin-7 antibody, RGD1562692 antibody, ataxin 7 L homeolog antibody, ataxin 7 antibody, atxn7.L antibody, atxn7 antibody, ATXN7 antibody, Atxn7 antibody
    背景

    Synonyms: Ataxin7, Ataxin-7, ADCAII, ATXN 7, OPCA III, OPCA3, SCA 7, SCA7, Spinocerebellar Ataxia 7, Spinocerebellar ataxia type 7 protein, ATX7_HUMAN.

    Background: The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).

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