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Endothelin 2 抗体 (AA 49-59) (AbBy Fluor® 350)

EDN2 适用: Cat IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1390329
发货至: 中国
  • 抗原 See all Endothelin 2 (EDN2) 抗体
    Endothelin 2 (EDN2)
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 49-59
    适用
    • 40
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Cat
    宿主
    • 51
    • 3
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 19
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endothelin 2 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 24
    • 20
    • 12
    • 12
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    Cat
    预测反应
    Human,Mouse,Rat,Dog,Cow,Cat,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Endolin 2
    亚型
    IgG
    Top Product
    Discover our top product EDN2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Endothelin 2 (EDN2)
    别名
    ET-2/Endothelin 2 (EDN2 产品)
    别名
    endothelin-2 antibody, EDN2 antibody, si:ch211-202b2.2 antibody, ET2 antibody, PPET2 antibody, VIC antibody, Et2 antibody, ET-2 antibody, endothelin 2 antibody, EDN2 antibody, edn2 antibody, Edn2 antibody
    背景

    Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.

    Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).

    途径
    Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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