GOPC 抗体 (AA 131-230) (AbBy Fluor® 350)
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- 抗原 See all GOPC 抗体
- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
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抗原表位
- AA 131-230
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GOPC antibody is conjugated to AbBy Fluor® 350
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PIST
- 亚型
- IgG
- Top Product
- Discover our top product GOPC Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
- 别名
- PIST/GOPC (GOPC 产品)
- 别名
- DKFZp459H2130 antibody, 2210402P09Rik antibody, AI844555 antibody, CAL antibody, FIG antibody, GOPC1 antibody, PIST antibody, fe38f01 antibody, wu:fe38f01 antibody, zgc:56254 antibody, zgc:65853 antibody, dJ94G16.2 antibody, cal antibody, gopc1 antibody, pist antibody, golgi associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing S homeolog antibody, GOPC antibody, Gopc antibody, gopc antibody, gopc.S antibody
- 背景
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Synonyms: CAL, CFTR associated ligand, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi associated PDZ and coiled coil mot containing, Golgi associated PDZ and coiled coil mot containing protein, Golgi-associated PDZ and coiled-coil mot-containing protein, GOPC, GOPC_HUMAN, GOPC1, OTTHUMP00000040403, PDZ protein interacting specically with TC 10, PDZ protein interacting specically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, PIST, Protein interacting specically with Tc 10, Protein interacting specically with Tc10, dJ94G16.2, dJ94G16.2 PIST.
Background: PIST (PDZ protein interacting specifically with TC10), also known as GOPC (golgi associated PDZ and coiled-coil motif containing), CAL or FIG, is a 462 amino acid protein that localizes to the cytoplasm, as well as to the membrane of the golgi apparatus and to the cell junction. Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Three isoforms of PIST exist due to alternative splicing events.
- 途径
- Maintenance of Protein Location, Asymmetric Protein Localization
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