RAB17 抗体 (AA 101-200) (Biotin)
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- 抗原 See all RAB17 抗体
- RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB17 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Rab17
- 亚型
- IgG
- Top Product
- Discover our top product RAB17 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
- 别名
- Rab17 (RAB17 产品)
- 别名
- RAB17 antibody, AW413472 antibody, RGD1562478 antibody, rab17 antibody, RAB17, member RAS oncogene family antibody, EDI_278050 antibody, EDI_260720 antibody, EDI_050010 antibody, RAB17 antibody, Rab17 antibody
- 背景
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Synonyms: Rab 17, Rab17, RAB17 member RAS oncogene family, RAB17_HUMAN, Ras related protein Rab 17, Ras related protein Rab17, Ras-related protein Rab-17, FLJ12538, OTTHUMP00000164417, OTTHUMP00000202805.
Background: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
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