NCAM2 抗体 (AA 51-150) (Biotin)
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- 抗原 See all NCAM2 抗体
- NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))
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抗原表位
- AA 51-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCAM2 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NCAM2
- 亚型
- IgG
- Top Product
- Discover our top product NCAM2 Primary Antibody
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- 应用备注
- ELISA 1:500-1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))
- 别名
- NCAM2 (NCAM2 产品)
- 别名
- NCAM21 antibody, Ncam-2 antibody, Ocam antibody, RNCAM antibody, zOCAM antibody, OCAM-GPI antibody, NCAM2 antibody, ncam21 antibody, neural cell adhesion molecule 2 antibody, zgc:152904 antibody, NCAM2 antibody, Ncam2 antibody, ncam2 antibody, LOC100471034 antibody, zgc:152904 antibody
- 背景
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Synonyms: N CAM 2, N CAM 21, N CAM2, N CAM21, N-CAM-2, NCAM 2, NCAM 21, NCAM-2, Ncam2, NCAM2_HUMAN, NCAM21, Neural cell adhesion molecule 2, OCAM GPI, R4B12, RB 8 neural cell adhesion molecule, RB8 neural cell adhesion molecule, RNCAM.
Background: NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.
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