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Junctophilin 3 抗体 (AA 181-280) (Biotin)

JPH3 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1389169
发货至: 中国
  • 抗原 See all Junctophilin 3 (JPH3) 抗体
    Junctophilin 3 (JPH3)
    抗原表位
    • 14
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 181-280
    适用
    • 28
    • 15
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Junctophilin 3 antibody is conjugated to Biotin
    应用范围
    • 29
    • 15
    • 13
    • 13
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Zebrafish
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Junctophilin 3
    亚型
    IgG
    Top Product
    Discover our top product JPH3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Junctophilin 3 (JPH3)
    别名
    Junctophilin 3 (JPH3 产品)
    别名
    CAGL237 antibody, HDL2 antibody, JP-3 antibody, JP3 antibody, TNRC22 antibody, Jp3 antibody, fc26e06 antibody, si:ch211-255l14.9 antibody, wu:fc26e06 antibody, junctophilin 3 antibody, JPH3 antibody, Jph3 antibody, jph3 antibody
    背景

    Synonyms: JP-3, JP3, JPH3, JPH3_HUMAN, Junctophilin3, Junctophilin type 3, Junctophilin-3, TNRC22, Trinucleotide repeat-containing gene 22 protein.

    Background: Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells. Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, as well as an ER/SR membrane spanning hydrophobic C-terminal segment. The three subtypes in this family are Junctophilin-1, -2 and -3. Junctophilin-1 is predominantly expressed in skeletal muscle, but is also expressed at low levels in heart. Junctophilin-2 is expressed in heart and skeletal muscle. Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients. Junctophilin-3 is expressed in brain. The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder.

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