Bestrophin 2 抗体 (AA 101-200) (AbBy Fluor® 350)
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- 抗原 See all Bestrophin 2 (BEST2) 抗体
- Bestrophin 2 (BEST2)
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Bestrophin 2 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Bestrophin 2
- 亚型
- IgG
- Top Product
- Discover our top product BEST2 Primary Antibody
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anti-Bestrophin 2 (BEST2) antibody
BEST2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 2 (BEST2) antibodyBEST2 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 2 (BEST2) (Internal Region) antibodyBEST2 适用: 人, 小鼠, 大鼠, 猴, Cow, Hamster, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 2 (BEST2) (Internal Region) antibodyBEST2 适用: 人, 猴, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 2 (BEST2) (3rd Extracellular Loop), (AA 259-270) antibodyBEST2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 2 (BEST2) (AA 374-403), (C-Term) antibodyBEST2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24342 unconjugated
anti-Bestrophin 2 (BEST2) (AA 381-411), (C-Term) antibodyBEST2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Bestrophin 2 (BEST2)
- 别名
- Bestrophin 2 (BEST2 产品)
- 别名
- VMD2L1 antibody, CG10173 antibody, Dmel\\CG10173 antibody, dbest2 antibody, Vmd2l1 antibody, best2 antibody, vmd2l1 antibody, MGC53680 antibody, MGC132361 antibody, Best2 antibody, GB16861 antibody, si:dkey-121b10.4 antibody, MGC75942 antibody, best2-a antibody, best2-b antibody, variant 2 antibody, bestrophin 2 antibody, Bestrophin 2 antibody, bestrophin 2 L homeolog antibody, uncharacterized LOC408898 antibody, bestrophin 2 S homeolog antibody, BEST2 antibody, Best2 antibody, best2.L antibody, LOC408898 antibody, best2 antibody, best2.S antibody
- 背景
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Synonyms: BEST 2, Best disease Bestrophin, BEST2, Bestrophin2, FLJ20132, Vitellorm macular dystrophy 2 homolog, Vitellorm macular dystrophy 2 like 1, Vitellorm macular dystrophy 2 like protein 1, Vitellorm macular dystrophy, VMD2, VMD2 like gene 1, VMD2L1, BEST2_HUMAN.
Background: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
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