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GLDN 抗体 (AA 365-460) (FITC)

GLDN 适用: 人, 小鼠, 大鼠 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal FITC
产品编号 ABIN1388870
发货至: 中国
  • 抗原 See all GLDN 抗体
    GLDN (Gliomedin (GLDN))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    AA 365-460
    适用
    • 35
    • 20
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 1
    克隆类型
    • 35
    多克隆
    标记
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLDN antibody is conjugated to FITC
    应用范围
    • 35
    • 17
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Gliomedin/COLM
    亚型
    IgG
    Top Product
    Discover our top product GLDN Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GLDN (Gliomedin (GLDN))
    别名
    Gliomedin (GLDN 产品)
    别名
    CLOM antibody, COLM antibody, CRG-L2 antibody, CRGL2 antibody, UNC-112 antibody, Clom antibody, Colm antibody, Crgl2 antibody, Crlg2 antibody, gliomedin antibody, GLDN antibody, Gldn antibody, gldn antibody
    背景

    Synonyms: CANCER RELATED GENE LIVER 2, Cancer related gene-Liver 2, CLOM, collomin, Colm gene name, COLM, Colmedin, CRG L2, FLJ23917, Gldn gene name, UNC 112, GLDN_HUMAN.

    Background: Gliomedin is a 551 amino acid protein encoded by the human gene GLDN. Gliomedin is thought to play a role in the formation of the nodes of Ranvier along myelinated axons. Accumulation of Na+ channels at the nodes of Ranvier is a prerequisite for saltatory conduction. In peripheral nerves, clustering of these channels along the axolemma is regulated by myelinating Schwann cells through an unknown mechanism. Gliomedin is a glial ligand for Neurofascin and NrCAM, two axonal immunoglobulin cell adhesion molecules that are associated with Na+ channels at the nodes of Ranvier. Gliomedin is expressed by myelinating Schwann cells and accumulates at the edges of each myelin segment during development, where it aligns with the forming nodes. Gliomedin is a single-pass type II membrane protein localized to the nodes of Ranvier and is specifically expressed in spinal cord, brain, placenta and sciatic nerve. It is more abundant in peripheral than central nervous system.

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