EDRF1 抗体
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- 抗原 See all EDRF1 (C10orf137) 抗体
- EDRF1 (C10orf137) (Chromosome 10 Open Reading Frame 137 (C10orf137))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDRF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EDRF1/C10orf137
- 亚型
- IgG
- Top Product
- Discover our top product C10orf137 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- EDRF1 (C10orf137) (Chromosome 10 Open Reading Frame 137 (C10orf137))
- 别名
- EDRF1 (C10orf137 产品)
- 别名
- EDRF1 antibody, AU022667 antibody, AW558805 antibody, Edrf1 antibody, erythroid differentiation regulatory factor 1 antibody, chromosome 10 open reading frame 137 antibody, EDRF1 antibody, C10orf137 antibody, Edrf1 antibody
- 背景
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Synonyms: C10orf137 protein, Chromosome 10 open reading frame 137, EDRF1, Erythroid dferentiation related factor 1, EDRF1_HUMAN.
Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.
- 基因ID
- 26098
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