KLHL36 抗体
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- 抗原 See all KLHL36 抗体
- KLHL36 (Kelch-Like 36 (KLHL36))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KLHL36 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KLHL36/C16orf44
- 亚型
- IgG
- Top Product
- Discover our top product KLHL36 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- KLHL36 (Kelch-Like 36 (KLHL36))
- 别名
- KLHL36 (KLHL36 产品)
- 别名
- C16orf44 antibody, C18H16orf44 antibody, zgc:110268 antibody, kelch like family member 36 antibody, kelch-like 36 antibody, kelch-like family member 36 antibody, KLHL36 antibody, Klhl36 antibody, klhl36 antibody
- 背景
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Synonyms: Kelch like 36, Kelch like protein 36, kelch-like 36 Drosophila, Kelch-like protein 36, KLH36_HUMAN, KLHL 36, KLHL-36.
Background: C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
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