LIN28A 抗体 (AA 65-160)
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- 抗原 See all LIN28A 抗体
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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抗原表位
- AA 65-160
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIN28A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Lin-28B
- 亚型
- IgG
- Top Product
- Discover our top product LIN28A Primary Antibody
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anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 108-138) antibody
LIN28A 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14827 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (N-Term) antibodyLIN28A 适用: 人, Pig, Cow, 犬, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 93-209) antibodyLIN28A 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 6D1F9 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 108-138) antibodyLIN28A 适用: 人, 小鼠 WB, ELISA, IF, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) antibodyLIN28A 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 168-198), (C-Term) antibodyLIN28A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14266 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 177-210), (C-Term) antibodyLIN28A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51168 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (C-Term) antibodyLIN28A 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) antibodyLIN28A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) antibodyLIN28A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- 别名
- Lin-28 (LIN28A 产品)
- 别名
- CSDD1 antibody, LIN-28 antibody, LIN28 antibody, ZCCHC1 antibody, lin-28A antibody, AL024421 antibody, ENSMUSG00000070700 antibody, Gm10299 antibody, Lin-28 antibody, Lin28 antibody, Tex17 antibody, csdd1 antibody, lin-28 antibody, lin28 antibody, zcchc1 antibody, sb:cb650 antibody, zgc:55584 antibody, RGD1566408 antibody, lin-28 homolog A antibody, lin-28 homolog A (C. elegans) antibody, lin-28 homolog A S homeolog antibody, LIN28A antibody, Lin28a antibody, lin28a.S antibody, lin28a antibody
- 背景
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Synonyms: Lin28B, CSDD 2, CSDD2, FLJ16517, Lin 28 homolog B C. elegans, Lin 28.2, Lin-28B, LIN28B, LN28B_HUMAN, Protein lin-28 homolog B, Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1.
Background: Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.
- 基因ID
- 389421, 79727
- UniProt
- Q6ZN17, Q9H9Z2
- 途径
- Stem Cell Maintenance
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