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FEZ2 抗体 (AA 165-240)

FEZ2 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387871
发货至: 中国
  • 抗原 See all FEZ2 抗体
    FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
    抗原表位
    • 14
    • 14
    • 7
    • 4
    • 1
    • 1
    • 1
    AA 165-240
    适用
    • 20
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FEZ2 antibody is un-conjugated
    应用范围
    • 35
    • 17
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FEZ2/Zygin2
    亚型
    IgG
    Top Product
    Discover our top product FEZ2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
    别名
    FEZ2/Zygin2 (FEZ2 产品)
    别名
    HUM3CL antibody, 9030616F16 antibody, D17Ertd315e antibody, Zrp antibody, fasciculation and elongation protein zeta 2 antibody, fasciculation and elongation protein zeta 2 (zygin II) antibody, FEZ2 antibody, Fez2 antibody
    背景

    Synonyms: Fasciculation and elongation protein zeta 2, Fasciculation and elongation protein zeta-2 , FEZ 2, Fez2, FEZ2_HUMAN, Highly similar to zyginII, HUM3CL, MGC117372, Pre T/NK cell associated protein, Zygin 2, Zygin II, Zygin-2.

    Background: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.

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