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PSMD6 抗体

PSMD6 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387855
发货至: 中国
  • 抗原 See all PSMD6 抗体
    PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))
    适用
    • 47
    • 33
    • 26
    • 6
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    • 4
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    人, 小鼠, 大鼠
    宿主
    • 46
    • 2
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 20
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    • 1
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    This PSMD6 antibody is un-conjugated
    应用范围
    • 39
    • 17
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PSMD6/Proteasome regulatory particle subunit p44S10
    亚型
    IgG
    Top Product
    Discover our top product PSMD6 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))
    别名
    PSMD6 (PSMD6 产品)
    别名
    Rpn7 antibody, S10 antibody, SGA-113M antibody, p42A antibody, p44S10 antibody, DDBDRAFT_0190867 antibody, DDBDRAFT_0232985 antibody, DDB_0190867 antibody, DDB_0232985 antibody, 2400006A19Rik antibody, P44s10 antibody, zgc:56471 antibody, p44s10 antibody, rpn7 antibody, s10 antibody, 141231_at antibody, CG5378 antibody, Dmel\\CG5378 antibody, S10a antibody, anon-WO0172774.103 antibody, anon-WO0172774.106 antibody, proteasome 26S subunit, non-ATPase 6 antibody, 26S proteasome non-ATPase regulatory subunit 6 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 antibody, proteasome 26S subunit, non-ATPase 6 S homeolog antibody, Regulatory particle non-ATPase 7 antibody, PSMD6 antibody, psmD6 antibody, Psmd6 antibody, psmd6 antibody, psmd6.S antibody, Rpn7 antibody, rpn-7 antibody
    背景

    Synonyms: 26S proteasome non-ATPase regulatory subunit 6, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit S10, Breast cancer-associated protein SGA-113M, KIAA0107, p42A, P44S10, PFAAP4, PSMD6_HUMAN, Phosphonoformate immuno-associated protein 4, Proteasome prosome, macropain 26S subunit, non-ATPase, 6, Proteasome regulatory particle subunit p44S10, Rpn7, S10 antibody SGA-113M.

    Background: In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation in vivo.

    基因ID
    9861
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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