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FAM126A 抗体 (AA 1-100)

FAM126A 适用: 人, 小鼠 WB, IF (p), IHC (fro), IHC (p), ELISA, ICC, IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387791
发货至: 中国
  • 抗原 See all FAM126A 抗体
    FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 8
    克隆类型
    • 8
    多克隆
    标记
    • 8
    This FAM126A antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Hyccin
    亚型
    IgG
    Top Product
    Discover our top product FAM126A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))
    别名
    FAM126A/Hyccin (FAM126A 产品)
    别名
    DRCTNNB1A antibody, HCC antibody, HLD5 antibody, HYCC1 antibody, AB030242 antibody, Drctnnb1a antibody, RGD1562906 antibody, zgc:77228 antibody, fam126a antibody, family with sequence similarity 126 member A antibody, family with sequence similarity 126, member A antibody, family with sequence similarity 126 member A S homeolog antibody, FAM126A antibody, Fam126a antibody, fam126a antibody, fam126a.S antibody
    背景

    Synonyms: Down regulated by Ctnnb1 a, Down regulated by CTNNB1 protein A, Down-regulated by CTNNB1 protein A, DRCTNNB1A, FAM126A, Family with sequence similarity 126 member A, HCC, HLD5, HYCC1, HYCCI_HUMAN antibody Hyccin, Protein FAM126A.

    Background: Hyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the -catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7.

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