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ADAM12 抗体 (AA 251-350)

ADAM12 适用: 人, 小鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387748
发货至: 中国
  • 抗原 See all ADAM12 抗体
    ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    适用
    • 34
    • 16
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 6
    • 3
    • 3
    克隆类型
    • 30
    • 5
    多克隆
    标记
    • 23
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM12 antibody is un-conjugated
    应用范围
    • 18
    • 14
    • 10
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ADAM12/MLTN
    亚型
    IgG
    Top Product
    Discover our top product ADAM12 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Branco, da Costa, Abe, Kataoka, Pinheiro, Alves Júnior: "HIF-1α, NOTCH1, ADAM12, and HB-EGF are overexpressed in mucoepidermoid carcinoma." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 127, Issue 1, pp. e8-e17, (2019) (PubMed).

  • 抗原
    ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))
    别名
    ADAM12 (ADAM12 产品)
    别名
    ADAM12 antibody, adam12 antibody, Mltna antibody, mKIAA4001 antibody, MCMP antibody, MCMPMltna antibody, MLTN antibody, MLTNA antibody, ADAM metallopeptidase domain 12 antibody, a disintegrin and metallopeptidase domain 12 (meltrin alpha) antibody, ADAM12 antibody, adam12 antibody, Adam12 antibody
    背景

    Synonyms: MLTN, A disintegrin and metalloproteinase domain 12, A disintegrin and metalloproteinase domain 12, ADA12_HUMAN, ADAM 12, ADAM metallopeptidase domain 12, ADAM12, Disintegrin and metalloproteinase domain-containing protein 12, MCMP, MCMPMltna, MCMPMltna, Meltrin alpha, Meltrin-alpha, MLTN, MLTNA, OTTHUMP00000046766.

    Background: ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).

    途径
    EGFR Signaling Pathway
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