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GBX2 抗体 (AA 251-348)

GBX2 适用: 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387700
发货至: 中国
  • 抗原 See all GBX2 抗体
    GBX2 (Gastrulation Brain Homeo Box 2 (GBX2))
    抗原表位
    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-348
    适用
    • 24
    • 19
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    大鼠
    宿主
    • 28
    • 10
    • 1
    克隆类型
    • 29
    • 10
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GBX2 antibody is un-conjugated
    应用范围
    • 31
    • 16
    • 13
    • 12
    • 12
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Gbx2
    亚型
    IgG
    Top Product
    Discover our top product GBX2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    GBX2 (Gastrulation Brain Homeo Box 2 (GBX2))
    别名
    Gbx2 (GBX2 产品)
    别名
    gbx-2 antibody, fd07f12 antibody, wu:fd07f12 antibody, GBX2 antibody, D130058E05Rik antibody, Gbx-2 antibody, MMoxA antibody, Stra7 antibody, gbx2 antibody, gastrulation brain homeobox 2 antibody, gastrulation brain homeobox 2, gene 2 L homeolog antibody, gbx2 antibody, GBX2 antibody, Gbx2 antibody, gbx2.2.L antibody
    背景

    Synonyms: Gastrulation and brain-specic homeobox protein 2, Gastrulation brain homeo box 2 , Gastrulation brain homeo box 2, gbx2, GBX2_HUMAN, Homeobox protein GBX 2 , Homeobox protein GBX 2, Homeobox protein GBX-2, Homeobox protein STRA7, Mmoxa.

    Background: The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes Gbx2 and Otx2. Gbx2 and Otx2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, Gbx2 negatively regulates Otx2 expression along the anterior-posterior axis, Gbx2(-) mutants demonstrate an expanded Otx2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. Gbx2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is over-expressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of Gbx2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that Gbx2 expression may be required for growth of malignant prostate cells.

    途径
    Dopaminergic Neurogenesis
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