MYLIP 抗体 (AA 65-103)
-
- 抗原 See all MYLIP 抗体
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
-
抗原表位
- AA 65-103
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MYLIP antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MYLIP
- 亚型
- IgG
- Top Product
- Discover our top product MYLIP Primary Antibody
-
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 111-139) antibody
MYLIP 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18661 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 266-445) antibodyMYLIP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Internal Region) antibodyMYLIP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 266-445) antibodyMYLIP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Internal Region) antibodyMYLIP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 440-475), (C-Term) antibodyMYLIP 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB47051 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) antibodyMYLIP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C10 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 360-409) antibodyMYLIP 适用: 人, 小鼠, 大鼠, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 161-210) antibodyMYLIP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- 别名
- MYLIP (MYLIP 产品)
- 别名
- IDOL antibody, MIR antibody, 9430057C20Rik antibody, Mir antibody, mylip antibody, wu:fj36b03 antibody, zgc:55987 antibody, MYLIP antibody, mir antibody, zgc:153767 antibody, myosin regulatory light chain interacting protein antibody, myosin regulatory light chain interacting protein a antibody, myosin regulatory light chain interacting protein L homeolog antibody, myosin regulatory light chain interacting protein b antibody, MYLIP antibody, Mylip antibody, mylipa antibody, mylip.L antibody, mylip antibody, mylipb antibody
- 背景
-
Synonyms: MIR, IDOL, E3 ubiquitin-protein ligase MYLIP, Inducible degrader of the LDL-receptor, Myosin regulatory light chain interacting protein, MYLIP, BZF1, BM-023, PP5242
Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
- 基因ID
- 29116
- UniProt
- Q8WY64
-
