SARM1 抗体 (AA 340-380)
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- 抗原 See all SARM1 抗体
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
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抗原表位
- AA 340-380
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SARM1
- 亚型
- IgG
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anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibody
SARM1 适用: 人, 小鼠 WB, IHC (p), IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) antibodySARM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
- 别名
- SARM1 (SARM1 产品)
- 别名
- A830091I15Rik antibody, C78606 antibody, MyD885 antibody, Sarm antibody, MyD88-5 antibody, SAMD2 antibody, SARM antibody, sterile alpha and TIR motif containing 1 antibody, sterile alpha and HEAT/Armadillo motif containing 1 antibody, SARM1 antibody, Sarm1 antibody, sarm1 antibody
- 背景
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Synonyms: SARM, SAMD2, MyD88-5, Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog, SARM1, KIAA0524
Background: Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
- 基因ID
- 23098
- UniProt
- Q6SZW1
- 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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