PEN2 抗体 (AA 6-80)
(1 reference)-
- 抗原 See all PEN2 (PSENEN) 抗体
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
-
抗原表位
- AA 6-80
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PEN2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Belongs to the PEN-2 family
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PEN2
- 亚型
- IgG
-
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 39-57) antibody
PSENEN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-101) antibodyPSENEN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12-G5 unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-50) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, 斑马鱼, 猴, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 20-69) antibodyPSENEN 适用: 人, 小鼠, 犬, 马, 豚鼠, 兔, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (N-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).
-
: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).
-
- 抗原
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
- 别名
- PEN2 (PSENEN 产品)
- 别名
- MSTP064 antibody, PEN-2 antibody, PEN2 antibody, Psenen antibody, ACYPI006208 antibody, 1700023M09Rik antibody, Pen-2 antibody, RGD1312037 antibody, CG33198 antibody, Dmel\\CG33198 antibody, anon-AE003800.1 antibody, dPen-2 antibody, psenen antibody, pen-2 antibody, pen2 antibody, zgc:109727 antibody, presenilin enhancer gamma-secretase subunit antibody, presenilin enhancer 2 antibody, presenilin enhancer gamma secretase subunit antibody, Gamma-secretase subunit pen-2 antibody, presenilin enhancer antibody, presenilin enhancer gamma secretase subunit S homeolog antibody, PSENEN antibody, PEN2 antibody, Psenen antibody, pen-2 antibody, psenen.S antibody, psenen antibody
- 背景
-
Synonyms: PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
- 基因ID
- 55851
- UniProt
- Q9NZ42
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
-
