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WWC1 抗体 (AA 351-450)

WWC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387477
发货至: 中国
  • 抗原 See all WWC1 抗体
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    抗原表位
    • 14
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    适用
    • 36
    • 19
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 3
    克隆类型
    • 34
    • 3
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWC1 antibody is un-conjugated
    应用范围
    • 37
    • 16
    • 12
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human KIBRA
    亚型
    IgG
    Top Product
    Discover our top product WWC1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    别名
    KIBRA (WWC1 产品)
    别名
    CG12600 antibody, CG33967 antibody, CG7552 antibody, Dmel\\CG33967 antibody, Kibra antibody, ORE-2 antibody, RE26350 antibody, kib antibody, l(3)02404 antibody, l(3)j5C3 antibody, l(3)neo42 antibody, HBEBP3 antibody, HBEBP36 antibody, KIBRA antibody, AA408228 antibody, AU017197 antibody, BC037006 antibody, mKIAA0869 antibody, CG33967 gene product from transcript CG33967-RB antibody, WW and C2 domain containing 1 antibody, WW, C2 and coiled-coil domain containing 1 antibody, kibra antibody, WWC1 antibody, Wwc1 antibody
    背景

    Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869

    Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

    基因ID
    23286
    UniProt
    Q8IX03
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