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CTH 抗体

CTH 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387469
发货至: 中国
  • 抗原 See all CTH 抗体
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    适用
    • 56
    • 33
    • 32
    • 5
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 10
    克隆类型
    • 50
    • 10
    多克隆
    标记
    • 31
    • 4
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    • 1
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    This CTH antibody is un-conjugated
    应用范围
    • 44
    • 16
    • 12
    • 11
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase
    亚型
    IgG
    Top Product
    Discover our top product CTH Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: "Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats." in: European journal of pharmacology, Vol. 771, pp. 123-9, (2016) (PubMed).

  • 抗原
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    别名
    CTH (CTH 产品)
    背景

    Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.

    Background: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

    基因ID
    1491
    途径
    ER-Nucleus Signaling, Warburg Effect
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