Mycobacterium Tuberculosis Ag85 抗体
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- 抗原
- Mycobacterium Tuberculosis Ag85
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适用
- Mycobacterium tuberculosis
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody will recognize Mycobacterium tuberculosis Ag85A and Ag85B
- 交叉反应
- Bacteria
- 交叉反应 （详细）
- Mycobacteriumtuberculosis
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B
- 亚型
- IgG
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anti-Mycobacterium Tuberculosis Ag85 antibody
适用: Bacteria WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Mycobacterium Tuberculosis Ag85
- 别名
- Mycobacterium Tuberculosis Ag85B
- 背景
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Synonyms: Antigen 85 complex B, 30 kDa extracellular protein, Mycobacterium, Mycolyl transferase 85B, fbpB, Antigen 85-B, 85B, Ag85B, Extracellular alpha-antigen, Fibronectin-binding protein B, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Ag85A, fbpA, 85A
Background: The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.
- 基因ID
- 885785, 886132
- UniProt
- P9WQP1, P9WQP3
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