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NAT8B 抗体 (AA 221-227)

NAT8B 适用: 人 WB, IF (p), IF (cc), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387301
发货至: 中国
  • 抗原 See all NAT8B 抗体
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    抗原表位
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 221-227
    适用
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 19
    • 1
    克隆类型
    • 19
    • 1
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAT8B antibody is un-conjugated
    应用范围
    • 19
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NAT8B
    亚型
    IgG
    Top Product
    Discover our top product NAT8B Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    别名
    NAT8B (NAT8B 产品)
    别名
    EG434057 antibody, Cml1 antibody, Cml6 antibody, Nat8 antibody, RGD621605 antibody, CML2 antibody, Hcml2 antibody, NAT8BP antibody, N-acetyltransferase 8B antibody, N-acetyltransferase 8B, pseudogene antibody, N-acetyltransferase 8B (putative, gene/pseudogene) antibody, NAT8B antibody, Nat8b-ps antibody, Nat8b antibody
    背景

    Synonyms: Camello like protein 2, Camello-like protein 2, CML2, Hcml2, N acetyltransferase 8B, NAT8B, NAT8B_HUMAN, NAT8BP, Probable N acetyltransferase 8B, Probable N-acetyltransferase 8B.

    Background: Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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