Dihydrofolate Reductase 抗体
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- 抗原 See all Dihydrofolate Reductase (DHFR) 抗体
- Dihydrofolate Reductase (DHFR)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Dihydrofolate Reductase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 纯化方法
- purified by Protein A and peptide affinity chromatography
- 免疫原
- KLH conjugated synthetic peptide derived from human DHFR
- 亚型
- IgG
- Top Product
- Discover our top product DHFR Primary Antibody
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- 应用备注
- WB (1:100-500),IHC-P (1:100-500),FACS (1:50-200),IF (p) (1:50-200)
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 µg/µL
- 缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C for 12 months
- 有效期
- 12 months
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- 抗原
- Dihydrofolate Reductase (DHFR)
- 别名
- DHFR (DHFR 产品)
- 别名
- DHFR antibody, F10_orf160 antibody, ECK0049 antibody, JW0047 antibody, tmrA antibody, cb595 antibody, zgc:86637 antibody, DDBDRAFT_0187132 antibody, DDBDRAFT_0230113 antibody, DDB_0187132 antibody, DDB_0230113 antibody, CG14887 antibody, Dmel\\CG14887 antibody, dhfr antibody, DHFRP1 antibody, DYR antibody, 8430436I03Rik antibody, AA607882 antibody, AI662710 antibody, AW555094 antibody, Dhfr1 antibody, confers resistance to sulfonamides antibody, dihydrofolate reductase antibody, dihydrofolate reductase DhfR antibody, Dihydrofolate reductase antibody, dhfr antibody, DHFR antibody, dhfR antibody, folA antibody, dfrA antibody, LOC707382 antibody, CNJ01940 antibody, DDB_G0286755 antibody, Dhfr antibody, Mesil_0096 antibody, Arch_0408 antibody, Fbal_3367 antibody, Ilyop_0482 antibody, Lbys_2007 antibody, Riean_0733 antibody, Mrub_1855 antibody, Poras_0766 antibody, Halhy_3552 antibody, Mesop_3614 antibody, LOC609048 antibody
- 背景
- DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.
- 分子量
- 21kDa
- 基因ID
- 1719
- HGNC
- 0
- 途径
- Mitotic G1-G1/S Phases
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