RNF20 抗体
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- 抗原 See all RNF20 抗体
- RNF20 (Ring Finger Protein 20 (RNF20))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF20 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF20
- 亚型
- IgG
- Top Product
- Discover our top product RNF20 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RNF20 (Ring Finger Protein 20 (RNF20))
- 别名
- RNF20 (RNF20 产品)
- 别名
- 4833430L21Rik antibody, AW540162 antibody, C79397 antibody, mKIAA4116 antibody, BRE1 antibody, BRE1A antibody, hBRE1 antibody, ring finger protein 20 antibody, RNF20 antibody, Rnf20 antibody
- 背景
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Synonyms: BRE1A, BRE1 A, E3 ubiquitin-protein ligase BRE1A, hBRE1, RING finger protein 20, BRE1A_HUMAN.
Background: RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
- 基因ID
- 56254
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