FKBP5 抗体 (AA 201-300)
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- 抗原 See all FKBP5 抗体
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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抗原表位
- AA 201-300
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FKBP5 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FKBP51
- 亚型
- IgG
- Top Product
- Discover our top product FKBP5 Primary Antibody
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anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibody
FKBP5 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibodyFKBP5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 308-457) antibodyFKBP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibodyFKBP5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3D1-1B10 unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D10-1G11 unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibodyFKBP5 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal Hi51B unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 326-375) antibodyFKBP5 适用: 人, 小鼠, 大鼠, 犬, 兔, Hamster, Cow, 马, 豚鼠, Pig, 斑马鱼, Bat, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibody (HRP)FKBP5 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal Hi51B HRP
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- 别名
- FKBP51 (FKBP5 产品)
- 别名
- FKBP5 antibody, FKBP-5 antibody, AIG6 antibody, FKBP51 antibody, FKBP54 antibody, P54 antibody, PPIase antibody, Ptg-10 antibody, D17Ertd592e antibody, Dit1 antibody, si:zc263a23.8 antibody, wu:fc31g11 antibody, wu:fl87b03 antibody, zgc:64082 antibody, FK506 binding protein 5 antibody, FKBP5 antibody, fkbp5 antibody, Fkbp5 antibody
- 背景
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Synonyms: FKBP 5, FKBP 51, FKBP 54, FKBP-5, FKBP-51, FKBP5, FKBP5_HUMAN, FKBP54, HSP90 binding immunophilin, HSP90-binding immunophilin, P54 antibody Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, PPIase, PPIase FKBP5, Ptg 10, Ptg10, Rotamase, T cell FK506 binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein, 51 kDa FK506-binding protein, 51 kDa FKBP, 54 kDa progesterone receptor associated immunophilin, 54 kDa progesterone receptor-associated immunophilin, AIG 6, AIG6, Androgen regulated protein 6, Androgen-regulated protein 6, FF1 antigen, FK506 binding protein 5, FK506-binding protein 5, MGC111006, OTTHUMP00000016268.
Background: The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin (1). Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin (2,3). The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4). FKBP51 and FKBP52 are two highly related proteins (5,6). FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5). FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation (7). FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
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