RPRD1B 抗体
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- 抗原 See all RPRD1B 抗体
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPRD1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CREPT
- 亚型
- IgG
- Top Product
- Discover our top product RPRD1B Primary Antibody
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anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 1-326) antibody
RPRD1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 2-172) antibodyRPRD1B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 143-192) antibodyRPRD1B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 小鸡, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 254-282), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25222 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 261-290), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
- 别名
- CREPT (RPRD1B 产品)
- 别名
- fb23h08 antibody, zgc:55687 antibody, wu:fb23h08 antibody, rprd1ba antibody, MGC130705 antibody, C13H20ORF77 antibody, C20orf77 antibody, CREPT antibody, NET60 antibody, dJ1057B20.2 antibody, 2610304G08Rik antibody, 2810446G03Rik antibody, Crept antibody, RGD1304782 antibody, regulation of nuclear pre-mRNA domain containing 1B antibody, regulation of nuclear pre-mRNA domain containing 1B L homeolog antibody, rprd1b antibody, rprd1b.L antibody, RPRD1B antibody, Rprd1b antibody
- 背景
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Synonyms: C20orf77, Cell cycle related and expression elevated protein in tumor, Chromosome 20 open reading frame 77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, Hypothetical protein LOC58490, Uncharacterized protein C20orf77, RPR1B_HUMAN.
Background: Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD.Transcriptional regulator which enhances expression of CCND1.Promotes binding of RNA polymerase II to the CCDN1 promoter and tothe termination region before the poly-A site but decreases itsbinding after the poly-A site. Prevents RNA polymerase II fromreading through the 3' end termination site and may allow it to berecruited back to the promoter through promotion of the formationof a chromatin loop. Also enhances the transcription of a number ofother cell cycle-related genes including CDK2, CDK4, CDK6 andcyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
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