SH2D1A 抗体
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- 抗原 See all SH2D1A 抗体
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SH2D1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SH2D1A/SAP
- 亚型
- IgG
- Top Product
- Discover our top product SH2D1A Primary Antibody
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anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibody
SH2D1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 11-124) antibodySH2D1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibodySH2D1A 适用: 人, 猴, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 18-115) antibodySH2D1A 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (Internal Region) antibodyVerified SH2D1A 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) antibodySH2D1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 85-114), (C-Term) antibodySH2D1A 适用: 人 WB 宿主: 兔 Polyclonal RB41923 unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibodySH2D1A 适用: 人, 大鼠, Pig, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- 别名
- SH2D1A (SH2D1A 产品)
- 别名
- DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
- 背景
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Synonyms: SH2 domain protein 1A, DSHP, Duncan disease SH2 protein, SAP, Signaling lymphocyte activation molecule associated protein, SLAM associated protein, T cell signal transduction molecule SAP, SH21A_HUMAN.
Background: SH2D1A, also SH2 domain protein 1A, SAP and CD150/SLAM (signaling lymphocyte activation molecule)-associated protein, influences signaling pathways involving SLAM molecules at the interface between T and B cells. SH2D1A modulates SLAM by blocking the recruitment of tyrosine phosphatase SHP2 to the phosphorylated cytoplasmic domain of SLAM. SLAM activation mediates expansion of activated T cells during immune responses, induces production of interferon-?and changes the functional profile of subsets of T cells. SH2D1A is a hydrophilic, 128 amino acid protein that is 96 % homologous to the mouse protein in both SH2 and tail domains. SH2D1A is present in all major subsets of T cells, including CD4+, CD45RO+, CD45RA+ and CD8+, but not in B cells. SH2D1A can interact via an SH2 domain with a motif (TIYXXV) present in the cytoplasmic tail of cell-surface receptors SLAM (CD150), CD84, CD229 (LY9) and CD244 (2B4).
- 基因ID
- 4068
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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