MYBPC3 抗体
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- 抗原 See all MYBPC3 抗体
- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYBPC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MYBPC3
- 亚型
- IgG
- Top Product
- Discover our top product MYBPC3 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
- 别名
- MYBPC3 (MYBPC3 产品)
- 别名
- MGC114614 antibody, hm:zehn0716 antibody, im:6900815 antibody, zgc:152717 antibody, zgc:158442 antibody, fhc antibody, cmh4 antibody, mybp-c antibody, CMH4 antibody, FHC antibody, MYBP-C antibody, myosin binding protein C, cardiac S homeolog antibody, myosin binding protein C, cardiac antibody, mybpc3.S antibody, MYBPC3 antibody, mybpc3 antibody, Mybpc3 antibody
- 背景
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Synonyms: C protein cardiac muscle isoform, cardiac muscle isoform, cardiac-type, C-protein, Cardiac MyBP C, Cardiac MyBP-C, Cardiac myosin binding protein C, MYBP C, MYBPC, MYBPC3, Myosin binding protein C cardiac, Myosin binding protein C cardiac-type, Myosin-binding protein C, MYPC3_HUMAN.
Background: MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.
- 基因ID
- 4607
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