ANKMY1 抗体
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- 抗原 See all ANKMY1 products
- ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANKMY1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ANKMY1
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))
- 别名
- ANKMY1 (ANKMY1 产品)
- 别名
- ZMYND13 antibody, 4930483I10Rik antibody, ankyrin repeat and MYND domain containing 1 antibody, ANKMY1 antibody, Ankmy1 antibody
- 背景
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Synonyms: ankyrin repeat and MYND domain containing 1, Testis specic ankyrin like protein 1, TSAL1, Zinc finger MYND domain containing protein 13, ZMYND13, ANKY1_HUMAN.
Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.
- 基因ID
- 51281
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