TSEN2 抗体
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- 抗原 See all TSEN2 抗体
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSEN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TSEN2
- 亚型
- IgG
- Top Product
- Discover our top product TSEN2 Primary Antibody
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anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibody
TSEN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-465) antibodyTSEN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 395-444) antibodyTSEN2 适用: 人, 兔, 犬, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
- 别名
- TSEN2 (TSEN2 产品)
- 别名
- AU067695 antibody, RGD1309946 antibody, PCH2B antibody, SEN2 antibody, SEN2L antibody, tRNA splicing endonuclease subunit 2 antibody, TSEN2 antibody, Tsen2 antibody
- 背景
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Synonyms: HsSen2, MGC2776, MGC4440, SEN2, SEN2L, tRNA intron endonuclease Sen2, tRNA splicing endonuclease 2 homolog SEN2, S. cerevisiae, tRNA splicing endonuclease subunit Sen2, TSEN 2, SEN2_HUMAN.
Background: The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5? and 3? splice sites, thereby releasing introns and free tRNA molecules with 2',3' cyclic phosphates and 5'-OH termini. In addition to its role in pre-tRNA splicing, the heterotetrameric endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. TSEN2 (tRNA-splicing endonuclease subunit Sen2), also known as tRNA-intron endonuclease Sen2, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex. There are three isoforms of TSEN2 that are produced as a result of alternative splicing events. Isoform 1 seems to carry the active site for 5?-splice site cleavage. Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, which is characterized by progressive microencephaly with epilepsy, extrapyramidal dyskinesia and chorea without spinal cord findings.
- 基因ID
- 80746
- 途径
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
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