E4F1 抗体
-
- 抗原 See all E4F1 抗体
- E4F1 (E4F Transcription Factor 1 (E4F1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This E4F1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human E4F1
- 亚型
- IgG
- Top Product
- Discover our top product E4F1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- E4F1 (E4F Transcription Factor 1 (E4F1))
- 别名
- E4F1 (E4F1 产品)
- 别名
- e4f antibody, MGC147041 antibody, E4F antibody, Dnase1l2 antibody, zgc:114190 antibody, E4F transcription factor 1 antibody, E4F transcription factor 1 S homeolog antibody, E4F1 antibody, e4f1 antibody, e4f1.S antibody, E4f1 antibody
- 背景
-
Synonyms: E4F, E4F transcription factor 1, isoform CRA_b, P120E4F transcription factor, E4F1_HUMAN.
Background: E4F1, also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains nine C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.
- 基因ID
- 1877
-