PDE4A 抗体
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- 抗原 See all PDE4A 抗体
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDE4A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PDE4A8
- 亚型
- IgG
- Top Product
- Discover our top product PDE4A Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
- Abstract
- PDE4A 产品
- 别名
- pde4 antibody, dpde2 antibody, pde46 antibody, PDE4A antibody, Pde4a antibody, D9Ertd60e antibody, Dpde2 antibody, DPDE2 antibody, PDE4 antibody, PDE46 antibody, PHOSA antibody, phosphodiesterase 4A S homeolog antibody, phosphodiesterase 4A, cAMP-specific antibody, phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) antibody, cAMP-specific 3',5'-cyclic phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP specific antibody, phosphodiesterase 4C antibody, pde4a.S antibody, pde4a antibody, PDE4A antibody, LOC100009247 antibody, Pde4a antibody, PDE4C antibody
- 背景
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Synonyms: 2EL, DPDE2, PDE4, PDE46, PDE4A, Phosphodiesterase 4A, Phosphodiesterse Type 4A8, PDE4A_HUMAN.
Background: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.
- 基因ID
- 5141
- 途径
- cAMP Metabolic Process
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