PIBF1 抗体
-
- 抗原 See all PIBF1 抗体
- PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PIBF1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PIBF1/C13orf24
- 亚型
- IgG
- Top Product
- Discover our top product PIBF1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))
- 别名
- PIBF1 (PIBF1 产品)
- 别名
- D14Ertd581e antibody, 1700017E21Rik antibody, 4930513H15Rik antibody, 4933438D16Rik antibody, 4933439E17Rik antibody, RGD1305077 antibody, PIBF antibody, C13orf24 antibody, zgc:101063 antibody, MGC80410 antibody, CEP90 antibody, RP11-505F3.1 antibody, progesterone immunomodulatory binding factor 1 antibody, progesterone immunomodulatory binding factor 1 S homeolog antibody, Pibf1 antibody, PIBF1 antibody, pibf1 antibody, pibf1.S antibody
- 背景
-
Synonyms: PIBF 1, PIBF, PIBF1, PIBF-1, Progesterone immunomodulatory binding factor 1, Progesterone induced blocking factor 1, Progesterone-Induced Blocking Factor 1, RP11 505F3.1, PIBF1_HUMAN, C13orf24.
Background: PIBF is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells). In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF is associated with the nucleus, whereas secretion of shorter forms is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines. The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites.
- 基因ID
- 10464
-