TNNI3K 抗体
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- 抗原 See all TNNI3K 抗体
- TNNI3K (TNNI3 Interacting Kinase (TNNI3K))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNNI3K antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TNNI3K
- 亚型
- IgG
- Top Product
- Discover our top product TNNI3K Primary Antibody
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anti-TNNI3 Interacting Kinase (TNNI3K) (AA 1-843) antibody
TNNI3K 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (AA 1-75) antibodyTNNI3K 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) antibodyTNNI3K 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (AA 1-75) antibodyTNNI3K 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (AA 755-804) antibodyTNNI3K 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (Internal Region) antibodyTNNI3K 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (AA 300-349) antibodyTNNI3K 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (AA 366-415) antibodyTNNI3K 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (N-Term) antibodyTNNI3K 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNNI3 Interacting Kinase (TNNI3K) (N-Term) antibodyTNNI3K 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TNNI3K (TNNI3 Interacting Kinase (TNNI3K))
- 别名
- TNNI3K (TNNI3K 产品)
- 别名
- CARK antibody, Cark antibody, D830019J24Rik antibody, TNNI3 interacting kinase antibody, serine/threonine-protein kinase TNNI3K antibody, TNNI3K antibody, LOC100592286 antibody, Tnni3k antibody
- 背景
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Synonyms: Cardiac ankyrin repeat kinase, CARK, MGC142099, MGC33828, Serine/threonine protein kinase TNN13K, Serine/threonine-protein kinase TNNI3K, TNI3K_HUMAN, TNNI3 interacting kinase, TNNI3-interacting kinase, Tnni3k.
Background: TNNI3K, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart. Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response. TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, therefore protecting the myocardium from ischemic injury. Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases. There are four isoforms of TNNI3K that are produced as a result of alternative splicing events.
- 基因ID
- 51086
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