TMIGD1 抗体 (AA 160-200)
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- 抗原 See all TMIGD1 抗体
- TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
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抗原表位
- AA 160-200
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMIGD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TMIGD1
- 亚型
- IgG
- Top Product
- Discover our top product TMIGD1 Primary Antibody
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anti-Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1) (AA 1-262) antibody
TMIGD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A8 unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
- 别名
- TMIGD1 (TMIGD1 产品)
- 别名
- RGD1307444 antibody, Tmigd antibody, TMIGD antibody, UNQ9372 antibody, 2010002A20Rik antibody, transmembrane and immunoglobulin domain containing 1 antibody, Tmigd1 antibody, TMIGD1 antibody
- 背景
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Synonyms: TMIGD, UNQ9372, Transmembrane and immunoglobulin domain-containing protein 1, TMIGD1, UNQ9372/PRO34164
Background: Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dub? syndrome and Canavan disease are also associated with chromosome 17.
- 基因ID
- 388364
- UniProt
- Q6UXZ0
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