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MID1 抗体 (AA 200-250)

MID1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387054
发货至: 中国
  • 抗原 See all MID1 抗体
    MID1 (Midline 1 (MID1))
    抗原表位
    • 14
    • 10
    • 10
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-250
    适用
    • 55
    • 33
    • 32
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 54
    • 2
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 26
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MID1 antibody is un-conjugated
    应用范围
    • 49
    • 21
    • 12
    • 8
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Midline-1/RNF59
    亚型
    IgG
    Top Product
    Discover our top product MID1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MID1 (Midline 1 (MID1))
    别名
    Midline-1 (MID1 产品)
    别名
    BBBG1 antibody, FXY antibody, GBBB1 antibody, MIDIN antibody, OGS1 antibody, OS antibody, OSX antibody, RNF59 antibody, TRIM18 antibody, XPRF antibody, ZNFXY antibody, 61B3-R antibody, DXHXS1141 antibody, Fxy antibody, Trim18 antibody, Midline1 antibody, bbbg1 antibody, fxy antibody, gbbb1 antibody, midin antibody, ogs1 antibody, osx antibody, rnf59 antibody, trim18 antibody, xprf antibody, znfxy antibody, midline 1 antibody, midline 1 L homeolog antibody, MID1 antibody, Mid1 antibody, mid1 antibody, mid1.L antibody
    背景

    Synonyms: BBBG1, Finger on X and Y mouse homolog of antibody, FXY, GBBB1, MID-1, Mid1, Midin, Midline 1 Opitz/BBB syndrome, Midline 1, Midline 1 ring finger, Midline 1 RING finger protein, Midline-1, Midline1, OGS1, OSX, Putative transcription factor XPRF, RING finger protein 59, RNF59, TRI18, TRI18_HUMAN, TRIM18, Tripartite mot containing protein 18, Tripartite mot protein TRIM18, Tripartite mot-containing protein 18, XPRF, Zinc finger X and Y antibody, ZNFXY.

    Background: Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.

    基因ID
    4281
    UniProt
    O15344
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