MARCH4 抗体
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- 抗原 See all MARCH4 抗体
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARCH4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MARCH4
- 亚型
- IgG
- Top Product
- Discover our top product MARCH4 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
- 别名
- MARCH4 (MARCH4 产品)
- 别名
- MARCH-IV antibody, RNF174 antibody, BC056494 antibody, mKIAA1399 antibody, MARCH4 antibody, si:ch211-239d11.2 antibody, membrane associated ring-CH-type finger 4 antibody, membrane-associated ring finger (C3HC4) 4 antibody, MARCH4 antibody, March4 antibody, march4 antibody
- 背景
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Synonyms: E3 ubiquitin protein ligase MARCH4, RNF174, KIAA1399, MARCH 4, MARCH IV, Membrane associated RING CH protein IV, Membrane associated ring finger C3HC4 4, Membrane associated RING finger protein 4, mKIAA1399, RING finger protein 174, MARH4_HUMAN.
Background: MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- 基因ID
- 57574
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