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MARCH2 抗体

MARCH2 适用: 人, 大鼠, 小鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387032
发货至: 中国
  • 抗原 See all MARCH2 抗体
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 33
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    克隆类型
    • 37
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    多克隆
    标记
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    This MARCH2 antibody is un-conjugated
    应用范围
    • 29
    • 12
    • 7
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    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MARCH2
    亚型
    IgG
    Top Product
    Discover our top product MARCH2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    别名
    MARCH2 (MARCH2 产品)
    别名
    MARCH-II antibody, RNF172 antibody, rgd1306395 antibody, marh2 antibody, RGD1306395 antibody, 9530046H09Rik antibody, membrane associated ring-CH-type finger 2 antibody, membrane associated ring-CH-type finger 2 S homeolog antibody, E3 ubiquitin-protein ligase MARCH2 antibody, membrane-associated ring finger (C3HC4) 2 antibody, MARCH2 antibody, march2.S antibody, march2 antibody, Tsp_09446 antibody, marh2 antibody, March2 antibody
    背景

    Synonyms: E3 ubiquitin protein ligase MARCH2, E3 ubiquitin-protein ligase MARCH2, EC 6.3.2.- antibody HSPC240, MARCH II, MARCH-II, march2, MARH2_HUMAN antibody Membrane associated RING CH protein II, Membrane associated ring finger C3HC4 2, Membrane associated RING finger protein 2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, RING finger protein 172, RNF172.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH2 (membrane-associated ring finger (C3HC4) 2), also known as RNF172 or HSPC240, is a 246 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one RING-CH-type zinc finger. Expressed in a variety of tissues, MARCH2 functions as an E3 ubiquitin-protein ligase that is thought to mediate the ubiquitination and subsequent degradation of CD71 and B7-2 and may be involved in endosomal protein trafficking.

    基因ID
    51257
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