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STIL 抗体

STIL 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387013
发货至: 中国
  • 抗原 See all STIL 抗体
    STIL (SCL/TAL1 Interrupting Locus (STIL))
    适用
    • 28
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    人, 小鼠, 大鼠
    宿主
    • 29
    克隆类型
    • 29
    多克隆
    标记
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    This STIL antibody is un-conjugated
    应用范围
    • 24
    • 12
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human STIL
    亚型
    IgG
    Top Product
    Discover our top product STIL Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    STIL (SCL/TAL1 Interrupting Locus (STIL))
    别名
    STIL (STIL 产品)
    别名
    Sil antibody, MCPH7 antibody, SIL antibody, chunp6907 antibody, sill antibody, zgc:110502 antibody, STIL, centriolar assembly protein antibody, Scl/Tal1 interrupting locus antibody, STIL, centriolar assembly protein L homeolog antibody, scl/tal1 interrupting locus antibody, Stil antibody, STIL antibody, stil.L antibody, stil antibody
    背景

    Synonyms: MCPH7, SCL interrupting locus protein, SCL-interrupting locus protein, SCL/TAL1 interrupting locus, SIL, STIL, STIL_HUMAN, TAL 1 interrupting locus protein, TAL-1-interrupting locus protein.

    Background: TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.

    基因ID
    6491
    途径
    Tube Formation
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