-
- 抗原 See all SASS6 抗体
- SASS6 (Spindle Assembly 6 Homolog (SASS6))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SASS6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SASS6
- 亚型
- IgG
- Top Product
- Discover our top product SASS6 Primary Antibody
-
anti-Spindle Assembly 6 Homolog (SASS6) (AA 1-490) antibody
SASS6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spindle Assembly 6 Homolog (SASS6) (AA 402-451) antibodySASS6 适用: 人, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SASS6 (Spindle Assembly 6 Homolog (SASS6))
- 别名
- SASS6 (SASS6 产品)
- 别名
- SAS-6 antibody, SAS6 antibody, 2810453L12Rik antibody, RGD1306255 antibody, CG15524 antibody, DSAS-6 antibody, DSas-6 antibody, DSas6 antibody, Dmel\\CG15524 antibody, Dsas6 antibody, Sas-6 antibody, Sas6 antibody, dsas-6 antibody, sas6 antibody, wu:fb98c12 antibody, zgc:55668 antibody, SASS6 antibody, sass6.2 antibody, SAS-6 centriolar assembly protein antibody, Spindle assembly abnormal 6 antibody, spindle assembly 6 homolog L homeolog antibody, SAS-6 centriolar assembly protein L homeolog antibody, SASS6 antibody, Sass6 antibody, Sas-6 antibody, sass6.L antibody, sass6 antibody, sass6.2.L antibody
- 背景
-
Synonyms: HsSAS 6, HsSAS6, MGC119440, SAS 6, SAS6, SASS 6, Spindle assembly 6 homolog C. elegans, Spindle assembly 6 homolog, Spindle assembly abnormal protein 6 homolog, PJA2_HUMAN.
Background: SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle, it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
- 基因ID
- 163786
-
You are here:
