RNF24 抗体
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- 抗原 See all RNF24 抗体
- RNF24 (Ring Finger Protein 24 (RNF24))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF24 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF24
- 亚型
- IgG
- Top Product
- Discover our top product RNF24 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RNF24 (Ring Finger Protein 24 (RNF24))
- 别名
- RNF24 (RNF24 产品)
- 别名
- G1L antibody, 2810473M14Rik antibody, 4930505A13Rik antibody, AI317164 antibody, C86507 antibody, D2Ertd504e antibody, ring finger protein 24 antibody, RNF24 antibody, Rnf24 antibody
- 背景
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Synonyms: G1L, Goliath-like protein C3HC4 type, RING finger protein 24, Rnf24, RNF24_HUMAN.
Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF24 (ring finger protein 24), also known as Goliath-like protein (C3CH4 type) or G1L, is a single-pass membrane protein found in the Golgi apparatus, consisting of 148 amino acids. RNF24 causes intracellular retention of TRPCs, regulates insertion of TRPCs into the plasma membrane and interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7. The RNF24 protein shares similarity with Drosophila Goliath protein and thus, may function as a transcription factor. Multiple transcript variants encoding different isoforms have been found for the RNF24 gene, which maps to human chromosome 20p13.
- 基因ID
- 11237
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