VGLL2 抗体
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- 抗原 See all VGLL2 抗体
- VGLL2 (Vestigial Like 2 (VGLL2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VGLL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human VGLL2
- 亚型
- IgG
- Top Product
- Discover our top product VGLL2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- VGLL2 (Vestigial Like 2 (VGLL2))
- 别名
- VGLL2 (VGLL2 产品)
- 别名
- VGL2 antibody, VITO1 antibody, vgll2a antibody, MGC114146 antibody, zgc:114146 antibody, C130057C21Rik antibody, VITO-1 antibody, Vito1 antibody, vgl-2 antibody, zgc:110098 antibody, vestigial like family member 2 antibody, vestigial-like family member 2 antibody, vestigial-like family member 2a antibody, vestigial like family member 2 L homeolog antibody, vestigial-like family member 2b antibody, VGLL2 antibody, Vgll2 antibody, vgll2a antibody, vgll2.L antibody, vgll2b antibody
- 背景
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Synonyms: Protein VITO1, Transcription cofactor vestigial like 2, Transcription cofactor vestigial like protein 2, Transcription cofactor vestigial-like protein 2, Vestigial like 2, Vestigial like 2 Drosophila, Vgl-2, VGL2, VGLL 2, Vgll2, VGLL2_HUMAN, VITO1.
Background: Vgl-2, also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus. Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.
- 基因ID
- 245806
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