RNF8 抗体
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- 抗原 See all RNF8 抗体
- RNF8 (Ring Finger Protein 8 (RNF8))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF8
- 亚型
- IgG
- Top Product
- Discover our top product RNF8 Primary Antibody
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anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibody
RNF8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (N-Term) antibodyVerified RNF8 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (C-Term) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (C-Term) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-260) antibodyRNF8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibodyRNF8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 351-400) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 335-364) antibodyRNF8 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibodyRNF8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-260) antibodyRNF8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RNF8 (Ring Finger Protein 8 (RNF8))
- 别名
- RNF8 (RNF8 产品)
- 别名
- hRNF8 antibody, 3830404E21Rik antibody, AIP37 antibody, RNF8 antibody, rnf8 antibody, fc66f09 antibody, wu:fc66f09 antibody, zgc:55936 antibody, zgc:77313 antibody, ring finger protein 8 antibody, ring finger protein 8, E3 ubiquitin protein ligase S homeolog antibody, ring finger protein 8, E3 ubiquitin protein ligase L homeolog antibody, ring finger protein 8, E3 ubiquitin protein ligase antibody, RNF8 antibody, Rnf8 antibody, rnf8.S antibody, rnf8.L antibody, rnf8 antibody
- 背景
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Synonyms: C3HC4 type zinc finger protein, E3 ubiquitin protein ligase RNF8, E3 ubiquitin-protein ligase RNF8, Ring finger protein C3HC4 type 8, RING finger protein 8, RNF 8, RNF8, RNF8_HUMAN, UBC13/UEV interacting ring finger protein.
Background: The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase. It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation. The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, and they co-localize in the nucleus. RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains. RNF8 also binds to Retinoid X receptor alpha (RXR?, a member of the steroid hormone receptor superfamily. It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity.
- 基因ID
- 9025
- 途径
- Production of Molecular Mediator of Immune Response
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