COPS4 抗体
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- 抗原 See all COPS4 抗体
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human COPS4
- 亚型
- IgG
- Top Product
- Discover our top product COPS4 Primary Antibody
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anti-COP9 Signalosome Subunit 4 (COPS4) (AA 1-310) antibody
COPS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 53-102) antibodyCOPS4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 143-192) antibodyCOPS4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, Pig, 斑马鱼, 小鸡, Bat, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (Middle Region) antibodyCOPS4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
- 别名
- COPS4 (COPS4 产品)
- 别名
- CG8725 antibody, CH4 antibody, Cops4 antibody, Csn4 antibody, DCH4 antibody, Dch4 antibody, Dmel\\CG8725 antibody, csn4 antibody, l(2)k08018 antibody, COPS4 antibody, SGN4 antibody, DKFZp459H0324 antibody, AW208976 antibody, D5Ertd774e antibody, fc90c08 antibody, wu:fc90c08 antibody, zgc:77137 antibody, ATS4 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 14 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 8 antibody, COP14 antibody, COP9 SIGNALOSOME SUBUNIT 4 antibody, CSN4 antibody, EMB134 antibody, EMBRYO DEFECTIVE 134 antibody, FUS4 antibody, FUS8 antibody, FUSCA 4 antibody, FUSCA 8 antibody, MBD2.17 antibody, MBD2_17 antibody, COS41.8 antibody, COP9 signalosome subunit 4 antibody, COP9 signalosome complex subunit 4 antibody, COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antibody, Proteasome component (PCI) domain protein antibody, COP9 signalosome subunit 4 L homeolog antibody, CSN4 antibody, COPS4 antibody, CpipJ_CPIJ000966 antibody, csn4 antibody, Cops4 antibody, cops4 antibody, COP8 antibody, cops4.L antibody, csn-4 antibody
- 背景
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Synonyms: CH4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 complex homolog subunit 4, COP9 complex S4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 signalosome complex subunit 4, COP9 signalosome subunit 4, COPS4, CSN complex subunit 4, CSN4, CSN4 SCHPO, CSN4_HUMAN, DCH4, JAB1 containing signalosome subunit 4, JAB1-containing signalosome subunit 4, MGC94896, SGN4, Signalosome subunit 4.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- 基因ID
- 51138
- 途径
- Cell Division Cycle
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